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Abstract
Peptic ulcer is a common disorder that affects the lives of millions of people every year. The predominant causes of peptic ulcer are infection with the bacterium called Helicobacter pylori (H. pylori) and the use of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). Chemical drugs used in the treatment of peptic ulcer produces side effects on long term use. Extensive research has been carried out in the area of treatment of ulcers through medicinal plants. Many medicinal plants have been reported to possess antiulcer activity. Effective plant extracts, screened by cytotoxic, genotoxic, toxicological parameters will lead to establishment as potent candidate for antiulcer drug development.
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References
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- Solanki, R. 2010. A review on medicinal plants with antiulceractivity.Int. J. pharm. Sci& Bio. 1(2): 67-70.
- Sravani, P., Jayasri, P., Samiulla, E.K.P., Nishad, K.P. 2011. Review in natural antiulcer agents. Int. J. Pharm & Ind. Res . 1:67-70.
- Wolfsthal, S.D. 2008. Medicine, 6th ed. Philadelphia, PA: NMS Medicine. 192-194.
- Zoetendal, E.G., Collier, C.T., Koike, S., Mackie, R.I., Gaskins, H.R. 2004. Molecular ecological analysis of the gastrointestinal microbiota: a review. J. Nutr.134(2): 465-472. DOI: https://doi.org/10.1093/jn/134.2.465
References
Anthony, J.D., Stanley, B.B. 2002. Gastrointestinal disease: an en-doscopic approach, 2nd ed. Thorofare, NJ: Slack Inc. 431-432.
Bethesda, M.D. 2010. H. pylori and Peptic Ulcers.National Di-gestive Diseases Information Clearinghouse, US FDA, NIH Publication No 10-4225.
Goroll, A.H., Mulley, A.G. 2009. Primary Care Medicine, 6th ed. Philadelphia, PA: Williams & Wilkins. 537-548.
Hooper, L.V., Gordon, J.I. 2001.Commensal host-bacterial relationships in the gut.Science, 292: 1115-1118. DOI: https://doi.org/10.1126/science.1058709
Kalliomäki, M., Salminen, S., Arvilommi, H., Kero, P., Koskinen, P., Isolauri, E. 2001. Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet.357: 1076-1079. DOI: https://doi.org/10.1016/S0140-6736(00)04259-8
Lawande,Y.S., Hase, R.S., Jadhav, D.P., Hyalij,T.A. 2011. Recent advances in research of antiulcer drug of natural origin: a review. Int. J. Pharm. Res. & Dev. 3(11): 160-170.
Ley, R.E., Peterson, D.A., Gordon, J.I. 2006.Ecological and evolutionary forces shaping microbial diversity in the human intestine.Cell,124: 837-848. DOI: https://doi.org/10.1016/j.cell.2006.02.017
Meyer, T. 2006. The Clinicians Guide to Acid peptic Disorder, 1st ed. Thorofare, NJ: Slack Inc. 151-180.
Ramakrishnan, K., Salinas, R.C. 2007.Peptic ulcer disease.Jay Siwek, MD: American Family Physician.76(7):1005–1012.
Salminen, S., Gueimonde, M., Isolauri, E. 2005. Probiotics that modify disease risk. J. Nutr., 135: 1294-1298. DOI: https://doi.org/10.1093/jn/135.5.1294
Saurabh, A., Mishra, A.S., Gupta ,S. 2012. A review on medicinal plant which may effective in the treatment of ulcer or which show anti ulcer activities.Int. J. Biopharm. Toxicological Res. 2:266-276.
Solanki, R. 2010. A review on medicinal plants with antiulceractivity.Int. J. pharm. Sci& Bio. 1(2): 67-70.
Sravani, P., Jayasri, P., Samiulla, E.K.P., Nishad, K.P. 2011. Review in natural antiulcer agents. Int. J. Pharm & Ind. Res . 1:67-70.
Wolfsthal, S.D. 2008. Medicine, 6th ed. Philadelphia, PA: NMS Medicine. 192-194.
Zoetendal, E.G., Collier, C.T., Koike, S., Mackie, R.I., Gaskins, H.R. 2004. Molecular ecological analysis of the gastrointestinal microbiota: a review. J. Nutr.134(2): 465-472. DOI: https://doi.org/10.1093/jn/134.2.465