Since ancient times, people explored the nature, chiefly plants in search of new drugs. This has resulted in the use of great number of medicinal plants with curative properties to treat a variety of diseases and hold medicinal significant bioactive compounds. Along with higher plants lower plants also posses this quality and bryophytes are just one of them as they are relatively free from microbial attacks which point toward their antimicrobial ability. Unfortunately, very little is known about the chemistry of bryophytes and information concerning research results is very scattered. Hence, preliminary phytochemical screening of different extracts (petroleum ether, acetone, methanol, chloroform, ethanol) of Plagiochasma appendiculatum and Dicranum scoparium was carried out along with total phenolic (GAE/ gm) and total flavonoid (mg QE/ gm) content of different extract of two tropical bryophytes, i.e. P. appendiculatum and D. scoparium using standard procedures, to identify the phytochemical constituents. The extracts were screened for the presence and quantities of total flavonoids and total phenols with a view to assess their therapeutic values in ethnomedicine. The results of the phytochemical screening revealed the presence of total flavonoids and total phenols in varying quantities in the two bryophytes. These results suggest that the undertaken bryophytes can be veritable and potential source of useful drugs in treatment of ailments.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
- Aiyelaagbe, O.O. and Osamudiamen, P.M., 2009. “Phytochemical screening for active compounds in Mangifera indica”, Plant Sciences Research, 2: 11-13.
- Aliyu, A.B., Ibrahim. H., Musa, A.M., Ibrahim. M.A., Oyevaleand. A.O., and Amupitan, J.O., 2010. “In Vitro Evaluation of Antioxidant Activity of Anisopus amannii”, African Journal of Biotechnogy, 9: 2437-2441.
- Asakawa, Y., 2007. “Biologically active compounds from bryophytes”, Pure Applied Chemistry, 79: 557-580.
- Asakawa, Y., 2011. “Bryophytes: Chemical Diversity, Synthesis and Biotechnology, A Review”, Flavor and Fragrance, 26: 318-320.
- Atmani, D., Chaher, N., Berboucha, M., Ayouni, K., Lounis, H., Boudaoud, H. and Debbache, N., 2009. “Antioxidant capacity and phenol content of selected Algerian medicinal plants”, Food Chemistry, 112: 303-309.
- Basile, A., S. Giordano, J. A., Lopez-Saez and Castaldo Cobianchi, R., 1999. “Antibacterial activity of pure flavonids isolated from mosses”, Phytochemistry, 52:1479-1482.
- Bhat, R., Ameran, S.B., Karim, A.A. and Liong, M.T., 2011. “Quality attributes of starfruit (Averrhoa carambola L.) juice treated with ultraviolet radiation”, Food Chemistry, 127:641-644.
- Chopra, R. S., 1975. “Taxonomy of Indian mosses”, Publication and information directorate (CSIR), New Delhi, :114.
- Cragg, G. M., and Newman, D. J. 2013. “Natural Products: A Continuing Source of Novel Drug Leads”,. Biochimica et Biophysica Acta, 1830(6), 3670–3695.
- Dhabhde, G. T., 1998. “Moss of Khandala and Mahabaleshwar in the Western ghats”, Classic graphics, Kalwa, Thane India,: 117-120.
- Evans., 2006. W.C. Pharmacology, 14th edn. Hart court Brace and Company, Asia Pvt. Ltd. Singapore.
- Gangulee, H. C., 1969. “Mosses of eastern India and adjacent regions”, Books and Allied Pvt. Ltd, Calcutta,:625-728.
- Goli, A. H., Barzegar, M. and Sahari, M. A., 2005. “Antioxidant activity and total phenolic compounds of pistachio (Pistachia vera) hull extracts”, Food Chemistry, 92: 521-525.
- Harborne, J. B., 1973. “Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis”, Chapman and Hull Ltd., London,:49-188.
- Hoareau, L. and DaSilva, E.J., 1999. “Medicinal plants: A re-emerging health aid. Electronic, Journal of Biotechnology, 2: 56-70.
- Khanam, Z., Wen, C. S. and Bhat, I. U. H., 2015. “Phytochemical screening and antimicrobial activity of root and stem extracts of wild Eurycoma longifolia Jack (Tongkat Ali)”, Journal of King Saud University-Science, 27: 23-30
- Krishnaiah, D., Sarbatly, R., and Bono, A., 2007. “Phytochemical antioxidants for health and medicine: A move towards nature”. Biotechnology and Molecular Biology Reviews, 1: 97-104.
- Luximon-Ramma, A., Bahorun, T. and Crozier, A., 2003. “Antioxidant actions and phenolic and vitamin C contents of common Mauritian exotic fruits”, Journal of the Science of Food and Agriculture, 83: 496-502.
- Marinova, D., Ribarova, F. and Atanassova, M., 2005. “Total phenolics and total flavonoids in Bulgarian fruits and vegetables”, Journal of Chemical Technology and Biotechnology, 40(3): 255-260.
- Merkuria, T., Steiner, U., Hindorf, H., J.P. Frahm, and Dehne, H.W., 2005. “Bioactivity of bryophyte extracts against Botrytis cinerea, Alternaria solani and Phytophtora infestans”, Journal of Applied Botany and Food Quality, 79: 89-93.
- Mohammad Reza, S. A., Mahnaz, K., Mannan, H., Maryam, J. and Abbas, H., 2010. “Comparison of antioxidant activity and total phenol contents of some date seed varieties from Iran” Iranian Journal of Pharmaceutical Research, 9(2): 141-146.
- Murugan, T., and Saranraj, P., 2011. “Antibacterial activity of various solvent extracts of the Indian herbal plant Acalypha indica against human pathogens causing nosocomial infection”, International Journal of Pharmaceutical and Biological Archives, 2(5): 1498 -1503
- Naczk, M. and Shahidi, F. 2006. “Phenolics in cereals, fruits, and vegetables: Occurrence, extraction, and analysis”, Journal of Pharmaceutical and Biomedical Analysis, 41: 1523-1542.
- Oki, T., Masuda, M., Furuta, S., Nishibia, Y., Terahara, N. and Suda, I., 2002. “Involvement of anthocyaninsand other phenolic compounds in radical-scavenging activity of purple-fleshed sweet potato cultivars”, Food and Chemical Toxicology, 67: 1752 -1756.
- Ramaan, N., 2006. “Phytochemical techniques”, New India Pub. Agency.
- Sabovljevic, A. Sabovljevic, M., 2008. “Bryophytes, a source of bioactive and new compounds”, Recent Progress in Medicinal Plants Vol. 22:Phytopharmacology and Therapeutic values IV, Studium Press LLC, TX, 9-25.
- Singh, S. and Srivastava, K., 2013. Bryophytes as Green Brain: Unique and Indispensable Small Creature. International Journal of Pharmaceutical Sciences Review and Research. 23(2):28-35.
- Singleton ,V.L., Orthofer. R., and Lamuela-Raventos, R.M., 1999. “Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent”, Methods in Enzymology, 299:152-178.
- Singleton, V.L. and Rossi, J., 1965. “Colorimetry of total phenolics with phosphomolybdic–phosphotungstic acid reagents”, The American Journal of Enology and Viticulture, 16:144–58.
- Smith, A. J. E., 1978. “The moss flora of Britain and Ireland”, Cambridge University Press, London,:271.
- Sofawara, A., 1993. “Medicinal Plants and Traditional Medicine in Africa”, Spectrum books Ltd., Ibadan Nigeria, : 191-289.
- Srivastava, K. and Singh S., 2007. “Pharmaceutical Products and anti-microbial activity of Bryophytes: Uses of Green Brain”. In: Medicinal Plants: Conservation, Cultivation and Utilization, Editors: A. K. Chopra, D. R. Khanna, G. Prasad, D. S. Malik and R. Bhutani.,Daya Publication House, New Delhi. :103-111.
- Sulaiman, C. T., Sadashiva, C. T., George, S., Goplakrishnan, V. K. and Balachandran, I., 2013. “Chromatographic studies and in vitro screening for acetyl cholinesterase inhibition and antioxidant activity of three Acacia species from South India”, Analytical Chemistry Letters, 3(2):111-118.
- Xie, C.F., and H. X. Lou., 2009. “Secondary metabolites in some bryophytes. An ecological aspect”, Chemistry and Biodiversity, 6: 303-312.