TY - JOUR AU - Chaudhary, Vishu AU - Katyal, Priya AU - Panwar, Harsh AU - Puniya, Anil Kumar AU - Poonia, Anuj Kumar PY - 2022/02/01 Y2 - 2024/03/29 TI - Evaluating anti-microbial and anti-oxidative potential of red biopigment from Monascus purpureus JF - Environment Conservation Journal JA - ECJ VL - 23 IS - 1&2 SE - Original Articles DO - 10.36953/ECJ.021833-2131 UR - https://journal.environcj.in/index.php/ecj/article/view/833 SP - 83-93 AB - <p><strong>In the present study, <em>Monascus </em>red biopigment produced by solid-state fermentation was evaluated for its anti-microbial and antioxidative potential. The antibacterial activity through Scanning Electron Microscopy against <em>Bacillus cereus</em>, <em>Escherichia coli</em>, and <em>Staphylococcus aureus </em>was found to show morphological damage in some cells, as evidenced by the outflow of cell contents, deep craters, burst cells, and cell death at concentration of 200 µg/ml of biopigment. Moreover, antibacterial activity through agar well diffusion method against <em>Bacillus cereus, Staphylococcus aureus, Klebsiella pneumonia </em>and <em>Pseudomonas aeruginosa </em>was in range of 2-6 mm by varying concentration of biopigment from 1 to 20 mg/ml.Next, the antifungal activity of the extracted biopigment was in the range of 2-9 mm for <em>Aspergillus flavus, Fusarium oxysporum </em>and <em>Alternaria alternata. </em>In addition, antioxidant efficacy of red biopigment through DPPH, ABTS and FRAP assay results was found to show 59.69 %, 91.1 %,  and 15.22 % free radical scavenging activity. The results of this study revealed that red biopigment has potential to modulate the antimicrobial and antioxidative activity.</strong></p> ER -