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January 2, 2014
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June 18, 2014
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Abstract

The hepatoprotective activity of methanolic rhizome extract of Curculigo orchioides (MECO) were evaluated against Thioacetamide-induced hepatic damage in rats. The MECO at dose of 100, 200 and 400 mg/kg were administered orally once daily for 21 days and simultaneously administered TAA 100 mg/kg b.w. s.c. 1 h after the respective assigned treatments every 72 h.  Serum enzymatic levels of serum glutamate oxaloacetate transaminase (AST), serum glutamate pyruvate transaminase (ALT), serum alkaline phosphatase (ALP) and total bilirubin were estimated along with estimation of superoxide dismutase (SOD) and malondialdehyde (MDA) levels in liver tissues.


 

Keywords

Amaryllidaceae Curculigo orchioides hepatoprotective silymarin thioacetamide

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Thapliyal , S. ., Juyal , V. ., & Bhandari , A. . (2014). Effect of rhizomes of Curculigo orchioides on Thioacetamide induced hepatotoxicity. Environment Conservation Journal, 15(1&2), 55–60. https://doi.org/10.36953/ECJ.2014.151207
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