Main Article Content

Abstract

The active  components  of stem  bark  of Tinospora cordifolia  were extracted  using  cold  water  and organic  solvents  (methanol,   diethyl  ether and  acetone)  and  were  tested  against  Staphylococcus aureus  using the agar disc diffusion  method.  All  the four extracts  inhibited  the growth of S.   aureus, with  methanol  extract  exerting the  highest  activity whereas  water  extract was  least active.  The results  were  compared  with  the  reference  antibiotic ciprofloxacin

Keywords

Antibacterial Tinospora cordifolia S. aureus Stem extract Methanol Diethyl ether Acetone.

Article Details

How to Cite
Deepika, Singh, P., & Upadhayay, V. (2009). Studies on antibacterial activity of extracts from Tinospora cordifolia (Giloy) against Staphylococcus aureus. Environment Conservation Journal, 10(1&2), 157–158. https://doi.org/10.36953/ECJ.2009.101228

References

  1. Bauer, A.W., Kirby, W.M.M., Sherris, J.C., and Turck, M.,1966. Antibiotic susceptibility testing by a standardized single disc method. American Journal of Clinical Pathology, 45: 493. DOI: https://doi.org/10.1093/ajcp/45.4_ts.493
  2. Chen, LN., Chang, C.C., Ng, C.C., Wang, C. Y., Shyu, Y.T., and Chang, TL, 2008. Antioxidant and antimicrobial activity of Zingiberaceae plants in Taiwan. Plant Foods Hum. Nutr., 63(1): 15-20. DOI: https://doi.org/10.1007/s11130-007-0063-7
  3. Guleria,S., and Kumar,A., (2006) : Antifungal activity of some Himalayan medicinal plants using direct bioautography. Journal of Cell and Molecular Biology.5:95-98.
  4. Nascimento, G.G.F., Locatelli, J., Freitas, P.C., and Silva G1., 2000. Antibacterial activity of plant extracts and phytochemicals on antibiotic resistant bacteria. Brazilian journal of Microbiology, 31: 247-256. DOI: https://doi.org/10.1590/S1517-83822000000400003
  5. Santos, PR.V., Oliveria, A.C.K., and Tomassini, T.C.B.,1995. Controle microbiogico de produtos fitoterapicos. Rev Farm. Bioquim, 31: 35-38.
  6. EIlof,J.N(1998). Which extract should be used for screening and isolation of antimicrobial components from plants. Ethnopharmacology, 60: 1-6. DOI: https://doi.org/10.1016/S0378-8741(97)00123-2
  7. Santos, F.D., Sarti, S.J., and Bastos, J.K., 1990. Atividade antibacteriana de extratos vegetias. Rev. Cien. Farm.,12: 39-46.
  8. Negi, KS. and Pant K.C., 1994. Genetic wealth of agro• horticultural crops, their wild relatives, indigenous, aromatic and medicinal plants of U.P Himalaya. J. Econ. & Tax. Bot., 18(1): 17-41.