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Abstract
The chronic effect of methyl parathion on cat fish Channa punctatus was observed by comparing the amount of urea & creatinine in the bio chemical blood plasma profile of a control group & a group exposed to methyl parathion pesticide, in sub lethal concentration. Lc50 value of fish was found 35µg/l. During the study it was found that the amount of urea in the experimental fish was increased upto alarming level, although the creatinine concentration increased gradually. As such fish food is consumed by the non target organisms & more specifically by the human being, its consumption usually results in the development of such symptoms, which are not mentioned in the routine literature.
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Funding data
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University Grants Commission
Grant numbers F-35-80/2008 (SR)
References
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References
APHA 1998. Standard methods for examination of water & waste water. 20th Edu. American Public Health Association, Washington D.C. PP 1976.
Anonymous, 2005. United States Environmental Protection Agency Technical Report. DOI: https://doi.org/10.2175/193864705783867675
Balis, M.E. 1976 Advances in Clinical Chemistry edited Bodansky, O. and Latner, A.L., Academic Press, London and New York, 18,213.
Baron D.N. and Huges G. 1965. Brit. Med. J, 1,233. DOI: https://doi.org/10.1136/bmj.1.5429.233
Bartels, H., Bohmer M., Heieruli, C. Clin. Chim. Acta, 1972, 37,193. DOI: https://doi.org/10.1016/0009-8981(72)90432-9
Begum, G., 2004. Carbofuran insecticide induced biochemical alterations in liver and muscle tissues of the fish Clarias batrachus (Linn.) and recovery response. Aquat. Toxicol. 66, 83-92. DOI: https://doi.org/10.1016/j.aquatox.2003.08.002
Bonsnes, R.W. and Taussjy, H.H. 1945. J. Biol. Chem., 158,581. DOI: https://doi.org/10.1016/S0021-9258(19)51334-5
Brod. J. and Sirota, J.H. 1948, J. Clin. Invest; 27,645. DOI: https://doi.org/10.1172/JCI102012
Burkepile, D.E., Moore, M.T., Holland, M.M., 2000. The susceptibility of five non target organisms to aqueous diazinon exposure, Bull Environ. Contam,. Toxicol., 64, 114-121. DOI: https://doi.org/10.1007/s001289910018
Ferrari, M.J. Ator, S.W. Blomquist, J.D. Dysart, J.E., 1997 Pesticides in surface water of the Mid-Atantic Region, U.S. Geological Survey Water-Resources Investigations Report 9797-4280, 20.
Hill, E.F. 2003. Wildife toxicology of organophosphorous and carbamate pesticides. In: Handbook of Ecotoxicology. (Hoffman, D.J., B.A. Ratner, G.A. Burton Jr. J. Cairns Jr., Eds.), Lewis Publishers, Boca Raton, pp. 281-312.
Kuivila, K.M., Foe, C.G, 1995. Concentrations, transport and biological effects of dormant spray pesticides in the San Fransisco Estuary, California. Environ. Toxicol,. Chem 14, 1141-1150. DOI: https://doi.org/10.1002/etc.5620140704
Meister, A.1965. Biochemistry of the Amino Acids, 2nd ed. Vol. 2, Academic Press.
Prakasam, A., S. Sethupathy and S. Lalitha, 2001. Plasma and RBCs antioxidant status in occupational male pesticide sprayers. Clin. Chim. Acta. 310, 107-112. DOI: https://doi.org/10.1016/S0009-8981(01)00487-9
Svodova, M., Luskova. V., Drastichova. J. and Zlabek, V., 2001. The effect of Diazinon on hematological. indices of common carp (Cypriuns carpio. L) Acta Vet.Brno., 70,457-465. DOI: https://doi.org/10.2754/avb200170040457
U.S. EPA, December, 2005. Office of Since and Thechnology Whashington, DC. Aquatic life ambient water quality critieria Diazinion Final. (CAS Registry Number 333-415).