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Abstract
The present study indicates that C and N sources are very important for antibiotic production. Streptomyces isolates DC-25 and DC-30 are specific to utilize C and N source for their growth. The compounds which have generally amino group is easily utilized by streptomyces and promote its growth for production of antibiotics by adding various amino acids like glycine, alanine, phenyl alanine, leucine and thyroxin. It was noted during course of study that various carbon sources like xylose, maltose, lactose etc. were utilized by actinomycetes but cellulose was poorly utilized.
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References
- Baldacci, E. 1961. The classification of actinomyces in relation to their antibiotic activity Adv. Appl. Microbial. 3; 257-277. DOI: https://doi.org/10.1016/S0065-2164(08)70512-4
- Basuchaudhary, K.C. 1961. Nutritional requirement of Streptomyces griseus on production of fungistatic substance. I. carbon source. Proc. Nat Acad. Sci India, Sec. B. 31: 268-272.
- Chestster, C.G.C and Rollinson G.N. 1955. Trace element and streptomycin production J.Gen. Microbiol. 5: 559-565. DOI: https://doi.org/10.1099/00221287-5-3-559
- Clutterbuck, P.W, Lovell, R. and Raistrich, H. 1932. Studies in biochemistry of Microorganism XXVI. The formation from glucose by member of P. chrysogenum an alkali soluble protein and penicillin. Antibiochem. J; 26. 1907-1918. DOI: https://doi.org/10.1042/bj0261907
- Dulany, E.L. 1948. Observation on S. griseus III on carbon sources for growth and streptomycin production. DOI: https://doi.org/10.2307/3755267
- Gupta, R.C. and Tandon, R.N. 1977, Growth inhibition of fungi form streptomycin trans, Brit My. Soci., 68(3): 438-439. DOI: https://doi.org/10.1016/S0007-1536(77)80199-X
References
Baldacci, E. 1961. The classification of actinomyces in relation to their antibiotic activity Adv. Appl. Microbial. 3; 257-277. DOI: https://doi.org/10.1016/S0065-2164(08)70512-4
Basuchaudhary, K.C. 1961. Nutritional requirement of Streptomyces griseus on production of fungistatic substance. I. carbon source. Proc. Nat Acad. Sci India, Sec. B. 31: 268-272.
Chestster, C.G.C and Rollinson G.N. 1955. Trace element and streptomycin production J.Gen. Microbiol. 5: 559-565. DOI: https://doi.org/10.1099/00221287-5-3-559
Clutterbuck, P.W, Lovell, R. and Raistrich, H. 1932. Studies in biochemistry of Microorganism XXVI. The formation from glucose by member of P. chrysogenum an alkali soluble protein and penicillin. Antibiochem. J; 26. 1907-1918. DOI: https://doi.org/10.1042/bj0261907
Dulany, E.L. 1948. Observation on S. griseus III on carbon sources for growth and streptomycin production. DOI: https://doi.org/10.2307/3755267
Gupta, R.C. and Tandon, R.N. 1977, Growth inhibition of fungi form streptomycin trans, Brit My. Soci., 68(3): 438-439. DOI: https://doi.org/10.1016/S0007-1536(77)80199-X