Main Article Content

Abstract

Pesticides constitute the important group of environmental pollutants since they are potent metabolic inhibitor. It is gradually being recognized that by use of natural herbs and herbal preparations in aquaculture we can deal with pesticidal  problems. The present study aimed to evaluate the characterization of ethanolic extract of Aloe vera (A.vera) by IR , SEM and to investigate its immunomodulatory,  antidiabetic and anticholesterol activity in H. fossilis after giving sublethal doses of fenvalerate. As blood is patho-physiological indicator, this study was performed to begin an assessment of the effect of fenvalerate on biochemistry of blood serum. In present study three sublethal doses of fenvalerate [0.25, 0.50 and 0.75 (p.p.m)] were given to test fish, H. fossilis for 15 days. After 15 days same fishes were given A.veraleafextract [(A.vera A) 250, (A.vera B) 500 and (A.vera C) 1000 (mg/kg of body wt.)] for 30 days to find its protection after intoxication of fenvalerate. Fenvalerate found harmfull in all the three doses and A.vera was protective against doses of fenvalerate.

Keywords

Aloe vera blood fenvalerate heteropneustes fossilis infrared spectroscopy SEM

Article Details

How to Cite
Mudgal, L., Joshi, P., & Sharma, R. (2012). Aloe vera extract characterization and its protection against fenvalerate induced toxicity in Heteropneustes fossilis. Environment Conservation Journal, 13(1&2), 65–71. https://doi.org/10.36953/ECJ.2012.131212

References

  1. Agnihotri, N.P., Jain, H.K.andGajbhiye, V.T., 1986. Persistence of some synthetic pyrethroid insecticides in soil, water and sediment - Part I. J. entomol. Res. 10(2): 147-151.
  2. Anderson, R.L., 1982. Toxicity offenvalerate and permethrin to several non-target aquatic invertebrates. Environ. Entomol.11: 1251-1257. DOI: https://doi.org/10.1093/ee/11.6.1251
  3. A.P.H.A., A.W.W.A. and W.P.C.F., 1992.Standard methods for the examination of water and wastewater.18th Ed. American Public Health Association. Washington.
  4. Bradbury, S.P. and Coats, J.R., 1982. Toxicity offenvalerate to bobwhite quail (Colinusvirginianus) including brain and liver residues associated with mortality. J. Toxicol. environ. Health,10: 307-319. DOI: https://doi.org/10.1080/15287398209530253
  5. Bunyapraphatsara, N., Yongchaiyudha, S., Rungpitarangsim, V., and Chokechaijaroenporn, O., 1996."Antidiabetic activity of Aloe vera L juice.II. Clinical trial in diabetes mellitus patients in combination with glibenclamide".Phytomedicine.,3: 245–248. DOI: https://doi.org/10.1016/S0944-7113(96)80061-4
  6. Can, A., Akev, N., Ozsoy, N., Bolkent, S., Arda, B.P., Yanardag, R andOkyar, A., 2004. Effect of Aloe vera leaf gel nd pulp extracts on the liver in type-II diabetic rat models.Biol.Pharm.Bull.,27(5):694-698. DOI: https://doi.org/10.1248/bpb.27.694
  7. Direkbusarakom, S., 2004. Application of medicinal herbs to aquaculture in Asia. WalailakJournal of Science and Technology,1(1): 7–14
  8. Ghannam, M. and Kingston, M., 1986.Antidiabetic activity of Aloes preliminary clinical and experimentalobservations. Horm. Res., 24(4):288-294. DOI: https://doi.org/10.1159/000180569
  9. Grover, J.K., YadA.vera, S., Vats, V., 2002. Medicinal plants of India with antidiabeticpotential. J. Ethnopharmacol., 81: 81–100. DOI: https://doi.org/10.1016/S0378-8741(02)00059-4
  10. Gupta, P.K. 1974. Malathion induced biochemical changes in rats. Acta.Pharmacol. Toxicol.,35:191-194. DOI: https://doi.org/10.1111/j.1600-0773.1974.tb00738.x
  11. Imanishi, K. Ishiguro, T., Saito, H. and Suzuki, I., 1981. Pharmacological studies on a plant lectin, Aloctin-A. I. Growth inhibition of mouse methyl cholanthrene induced fibrosarcoma (Metha A) in ascites form by Aloctin-A. Experientia.,37:1186-1187. DOI: https://doi.org/10.1007/BF01989910
  12. Joshi, S. Dixit, V.P., 1983. Effect Of Aloe and Colfibrate On Serum Lipids In Hyperlipidemia In Presbytis Monkeys.Indian Journal of Medical Research,78:417-421.
  13. Joshi, S. Dixit, V.P. (1986): Hypolipidemia effect of Aloe barbadensis (Aloe fraction I) in cholesterol-fed rats. I. Lipid and lipoprotein metabolism. Proc. Nat. Acad. Sci. India, Sect. B (Biol. Sci.).56:339-342.
  14. Khan, A. and Haleem D.J., 2006. The protective effect of aloe vera juice on lindane induced hepatotoxicity and genotoxicity. Pak. J. Pharm. Sci.19(4), 337-340.
  15. Murray,R.K., 1991. Harpers Biochemistry 22ndedition Prentice Hall International Inc. 678.
  16. Pittman, J.C.,1992. Immune enhancing effects of Aloe.,Health Conscious.,13(1): 28-30.
  17. Radhiah, V. and Jayantha, Rao. 1992.Fenvalerate toxicity to the liver in a fresh water teleost, Tilapia mossambica(peters). Comp. Physiol. Ecol.,17(2):930-932.
  18. Reddy, M. and Bashamohideen.1988. Toxic impact of fenvalerate on the protein metabolism in the branchial tissue of a fish, Cyprinus carpio, Current Science, 57(4):211-212.
  19. Reddy, Dr. P. Malla., Bashamohideen Md., 2006. Fenvalerate and Cypermethrin Induced Changes in the Haematological Parameters of Cyprinus carpio.17(1):101-107. DOI: https://doi.org/10.1002/aheh.19890170116
  20. Sheets, Mark. A., Unger, Beverly. A., Giggleman, Gene. F. Jr. and Tizzard, Ian. R. 1991. Studies on the effect of Acemannan on retrovirus infections: clinicalstabilization of feline leukemia virus-infected cats. Molecular Biotherapy,3:41-45.
  21. Stepanova, O.S., Prudnik. N.Z., Solov’eva, V.P., Golovchenko, G.A., Svishchuk, A.A., Grin, Erg, B.G. and Dubkova, O.M.,1977. Chemical composition and biological activity of dry Aloe leA.veraes.Fiziol.Akt. Veshchestva.,9: 94-97.
  22. Suzuki, I., 1979. Anti-cancer substances from Aloe.Jpn. Kokai.TokkyoKoho.,79,84:081. DOI: https://doi.org/10.3861/jshhe.45.79
  23. Worthing, C.R. and Walker, S.B., 1987. Fenvalerate In: The pesticide manual, 8th ed., Croydon, British Crop Protection Council : 395-396
  24. Wszolek, P.C., Hogue, D.E., and Lisk, D.J., 1981a. Accumulation offen valerate insecticide in lamb tissues.Bull. environ. Contam.Toxicol.,27: 869-871 DOI: https://doi.org/10.1007/BF01611109
  25. Yagi, A., 1987.Effect of Amino Acids in Aloe Extract on Phagocytosis by peripheral neutrophils in Adult Bronchial Asthma.Jpn J. Allegrol., 36 (12):1094-1101