Main Article Content

Abstract

Terminalia bellirica is one of the high traded medicinal plant species, mainly known for its fruits which are bestowed with numerous biological activities and used in treatment of various ailments. The fruits are one of three ingredients of well-known Ayurvedic formulation ‘TRIPHLA’. The purpose of this study was to determine the variations for Gallic acid (GA), a chemical marker compound, as well as for key morphological traits (height, girth at breast height, clear bole height, fruit size) in trees from central Indian states viz. Madhya Pradesh, Chhattisgarh and Maharashtra. In this investigation, we also explored the correlation between the chemical marker and morphological features. The study suggested the maximum GA content (0.98±0.42%) in populations of Keregaon range of Dhamtari forest division of Chhattisgarh state which can be considered as superior chemotypes/ populations. The correlation analysis exhibited the positive association between fruit size and GA content.

Keywords

Terminalia bellirica Chemical and morphological variations Gallic acid Correlation Central India

Article Details

How to Cite
Saxena, H., Kobragade, N. D., Parihar, S. ., Kundu, M., Rao, G. R., & Pawar, G. (2022). Chemical and morphological variations in Terminalia bellirica (Gaertn.) Roxb. – a species of commercial ayurvedic formulation triphla from central India. Environment Conservation Journal, 23(1&2), 410–416. https://doi.org/10.36953/ECJ.0211162.2305

References

  1. Akinmoladun, A.C., Ibukun, E.O., Afor, E., Obuotor, E.M., Farombi, E.O. (2007). Phytochemical constituent and antioxidant activity of extract from the leaves of Ocimum gratissimum. Scientific Research and Essays, 2: 163-6. https://doi.org/10.5897/SRE.9000731
  2. Bai, J., Zhang, Y., Tang, C., Hou, Y. Ai. X., Chen, X., Zhang, Y., Wang, X., Meng, X. (2021). Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases. Biomédecine & pharmacothérapie, 133:110985. https://doi.org/10.1016/j.biopha.2020.110985 DOI: https://doi.org/10.1016/j.biopha.2020.110985
  3. Chatterjee, A., Chatterjee, S., Biswas, A., Bhattacharya, S., Chattopadhyay, S., Bandyopadhyay, S.K. (2012). Gallic acid enriched fraction of Phyllanthus emblica potentiates indomethacin-induced gastric ulcer healing via e-NOS-dependent pathway. Evid -based Complement Alter. https://doi.org/10.1155/2012/487380 DOI: https://doi.org/10.1155/2012/487380
  4. Deb, A., Barua, S., Das, B. (2019). Pharmacological activities of Baheda (Terminalia bellerica): a review. Journal of Pharmacognosy and Phytochemistry 5(1):194.
  5. Fernandes, F.H., Salgado, H.R. (2016) Gallic acid: review of the methods of determination and quantification. Critical Reviews in Analytical Chemistry, 46:257-65. https://doi.org/10.1080/10408347.2015.1095064 DOI: https://doi.org/10.1080/10408347.2015.1095064
  6. Gandhi, G.R., Jothi, G., Antony, P.J., Balakrishna, K., Paulraj, M.G., Ignacimuthu, S., Stalin, A., Al-Dhabi, N.A. (2014). Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPAR? in experimental type 2 diabetic rats and enhances glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway. European journal of pharmacology 745:201-16.https://doi.org/10.1016/j.ejphar.2014.10.044 DOI: https://doi.org/10.1016/j.ejphar.2014.10.044
  7. Gupta, A., Kumar, R., Kumar, S., Pandey, A.K (2017). Pharmacological aspects of Terminalia bellirica. Molecular Biology and Pharmacognosy of Beneficial Plants. AA Mahdi, M. Abid, MMAA Khan, MI Ansari, RK Maheshwari (Eds) Lenin Media Private Limited: Delhi, India. 52-64.
  8. Gupta, A.K., Tandon, N., Sharma, M. (2003). Quality Standards of Indian Medicinal Plants. An ICMR Publication, New Delhi.1:198-209.
  9. Joshi, D.D., Uniyal, R.C. (2008). Different chemo types of Gokhru (Tribulus terrestris): A herb used for improving physique and physical performance. International Journal of Green Pharmacy, 2: 158-61. DOI:10.4103/0973-8258.42734 DOI: https://doi.org/10.4103/0973-8258.42734
  10. Kahkeshani, N., Farzaei, F., Fotouhi, M., Alavi, S.S, Bahramsoltani, R., Naseri, R., Momtaz, S., Abbasabadi, Z., Rahimi, R., Farzaei, M.H., Bishayee, A. (2019). Pharmacological effects of gallic acid in health and diseases: A mechanistic review. Iranian Journal of Basic Medical Sciences, 22:225. doi: 10.22038/ijbms.2019.32806.7897
  11. Kaushik, S., Sharma, P., Jain, A. and Sikarwar, M.S. (2010). Preliminary phytochemical screening and HPTLC fingerprinting of Nicotiana tabacum leaf. Journal of Pharmacy Research, 3(5): 1144-1145.
  12. Ketsa, S. (1988). Effects of fruit size on juice content and chemical composition of tangerine. Journal of Horticultural Science, 63(1): 171-174. DOI: https://doi.org/10.1080/14620316.1988.11515843
  13. Mohammad, N., Sonkar, M., Pardhi, Y., Rana, P.K. and Dahayat, A. (2020. Assessment of morphological variation and association studies in Litsea glutinosa (Lour.) CB Rob. from Central India. Journal of Sustainable Forestry, 39(2): 207-220. https://doi.org/10.1080/10549811.2019.1632720 DOI: https://doi.org/10.1080/10549811.2019.1632720
  14. Nagpal, K., Singh, S.K., Mishra, D.N. (2013) Nanoparticle mediated brain targeted delivery of gallic acid: in vivo behavioral and biochemical studies for protection against scopolamine-induced amnesia. Drug Delivery 20:112-9. https://doi.org/10.3109/10717544.2012.738437 DOI: https://doi.org/10.3109/10717544.2013.779330
  15. NMPB (2022). https://nmpb.nic.in/medicinal_list
  16. Mallik, J., Das, P., Karon, B. and Das, S. (2012). A review on phytochemistry and pharmacological activity of Terminalia bellirica. International Journal of Drug Formulation and Research, 3(6): 1-5.
  17. Omojate, G.C., Enwa, F.O., Jewo, A.O., Eze C.O. (2014) Mechanisms of antimicrobial actions of phytochemicals against enteric pathogens–a review. Journal of Pharmaceutical, Chemical and Biological Sciences, 2:77-85.
  18. Priscilla, D.H. and Prince, P.S.M. (2009). Cardioprotective effect of gallic acid on cardiac troponin-T, cardiac marker enzymes, lipid peroxidation products and antioxidants in experimentally induced myocardial infarction in Wistar rats. Chemico-Biological Interactions, 179(2-3): 118-124. https://doi.org/10.1016/j.cbi.2008.12.012 DOI: https://doi.org/10.1016/j.cbi.2008.12.012
  19. Saxena, H.O., Maolankar, S., Madave, R., Soni, A. and Gupta, R. (2015). Quantification of phenolic acids in fruits of Solanum xanthocarpum from three agroclimatic regions of Madhya Pradesh using HPLC. Indian Journal Tropical Biodiversity, 23(1): 46-52.
  20. Usenik, V., Stampar, F., Petkovsek, M.M. and Kastelec, D. (2015). The effect of fruit size and fruit colour on chemical composition in ‘Kordia’sweet cherry (Prunus avium L.). Journal of Food Composition and Analysis, 38: 121-130. http://dx.doi.org/10.1016/j.jfca.2014.10.007 DOI: https://doi.org/10.1016/j.jfca.2014.10.007
  21. Vasudevan, H. (2009). DNA fingerprinting in the standardization of Herbs and Nutraceuticals. The Science Creative Quaterly, 4.
  22. Zhang, X.R., Kaunda, J.S., Zhu, H.T., Wang, D., Yang, C.R., & Zhang, Y.J. (2019). The genus Terminalia (Combretaceae): An ethnopharmacological, phytochemical and pharmacological review. Natural Products and Bioprospecting, 9(6): 357-392. https://doi.org/10.1007/s13659-019-00222-3 DOI: https://doi.org/10.1007/s13659-019-00222-3